Publications

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Currently displaying 1 - 20 of 257 publications

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana

Chemistry (Weinheim an der Bergstrasse, Germany)

(2025)

e202501286

(doi: 10.1002/chem.202501286)

An Expanded View of RNA Modification with Carbohydrate-Based Metabolic Probes

ME Hazemi, MB Geeson, FM Müller, S Mikutis, AJ Enright, GJL Bernardes

Jacs Au

(2025)

2309

(doi: 10.1021/jacsau.5c00249)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

BH Gless, E Jones, C Labão-Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angewandte Chemie International Edition

(2025)

e202502268

(doi: 10.1002/anie.202502268)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

G Lopes Bernardes, B Gless, E Jones

Angewandte Chemie

(2025)

137

(doi: 10.1002/ange.202502268)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

BH Gless, E Jones, C Labão‐Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angewandte Chemie

(2025)

137

e202502268

(doi: 10.1002/ange.202502268)

Bifunctional Phagocytic Synapse Enhancers for Cancer Immunotherapy

V Sabatino, S Fleisch, C Tang, FM Müller, C Labão-Almeida, WT Khaw, S Hogan, DR Hicks, M Fontes, AR Coelho, W Yang, I Sarkar, D Shome, AV Vidal, M Cabeza-Cabrerizo, T Rohm, RM Reijmers, D Kaymak, F Gerster, D Baker, R Fior, G Hutter, GJL Bernardes

(2025)

(doi: 10.1101/2025.03.13.642658)

Correction to "Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform".

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Anal Chem

(2025)

4251

(doi: 10.1021/acs.analchem.5c00703)

Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Analytical chemistry

(2024)

290

(doi: 10.1021/acs.analchem.4c04188)

Site-Specific Quadruple-Functionalised Antibodies.

T Journeaux, MB Geeson, TV Murray, MA Papworth, M Gothard, JG Kettle, AV Vasco, GJL Bernardes

Angewandte Chemie (International ed. in English)

(2024)

e202417620

(doi: 10.1002/anie.202417620)

Technologies for Targeted RNA Degradation and Induced RNA Decay

S Mikutis, GJL Bernardes

Chemical Reviews

(2024)

124

13301

(doi: 10.1021/acs.chemrev.4c00472)

Non‐Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity

A Guerreiro, I Compañón, FS Lazaris, C Labão-Almeida, P Oroz, M Ghirardello, MC Marques, F Corzana, GJL Bernardes

Angewandte Chemie International Edition

(2024)

e202411009

(doi: 10.1002/anie.202411009)

Small Molecule RNA Degraders.

J Bonet-Aleta, T Maehara, BA Craig, GJL Bernardes

Angewandte Chemie International Edition

(2024)

e202412925

(doi: 10.1002/anie.202412925)

Designed endocytosis-inducing proteins degrade targets and amplify signals

B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, T Schlichthaerle, JZ Zhang, Y Wang, I Goreshnik, CW Chiu, A Chazin-Gray, S Chan, S Gerben, A Murray, S Wang, J O'Neill, L Yi, R Yeh, A Misquith, A Wolf, LM Tomasovic, DI Piraner, MJ Duran Gonzalez, NR Bennett, P Venkatesh, M Ahlrichs, C Dobbins, W Yang, X Wang, DD Sahtoe, D Vafeados, R Mout, S Shivaei, L Cao, L Carter, L Stewart, JB Spangler, KT Roybal, PJ Greisen, X Li, GJL Bernardes, CR Bertozzi, D Baker

Nature

(2024)

638

(doi: 10.1038/s41586-024-07948-2)

Proximity-driven site-specific cyclization of phage-displayed peptides.

L Brown, AV Vidal, AL Dias, T Rodrigues, A Sigurdardottir, T Journeaux, S O'Brien, TV Murray, P Ravn, M Papworth, GJL Bernardes

Nature Communications

(2024)

7308

(doi: 10.1038/s41467-024-51610-4)

Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution

VB Unnikrishnan, V Sabatino, F Amorim, MF Estrada, CD Navo, G Jimenez-Oses, R Fior, GJL Bernardes

Journal of the American Chemical Society

(2024)

146

23240

(doi: 10.1021/jacs.4c05582)

On-demand thio-succinimide hydrolysis for the assembly of stable protein–protein conjugates

AV Vasco, RJ Taylor, Y Méndez, GJL Bernardes

J Am Chem Soc

(2024)

146

20709

(doi: 10.1021/jacs.4c03721)

Homogeneous multi-payload antibody-drug conjugates.

T Journeaux, GJL Bernardes

Nature Chemistry

(2024)

854

(doi: 10.1038/s41557-024-01507-y)

Targeted protein editing with an antibody-based system

M Vendruscolo, O Rimon, J Konc, M Ali, VR Chowdhury, P Sormanni, G Bernardes

(2024)

(doi: 10.21203/rs.3.rs-3947849/v1)

Cathepsin B Processing is Required for the in vivo Efficacy of Albumin-Drug Conjugates

B Bernardim, J Conde, T Hakala, JB Becher, M Canzano, AV Vasco, TPJ Knowles, J Cameron, GJL Bernardes

Bioconjugate chemistry

(2024)

132

(doi: 10.1021/acs.bioconjchem.3c00478)

Design and Evaluation of PROTACs Targeting Acyl Protein Thioesterase 1

G Lopes Bernardes

Chembiochem

(2024)

e202300736

(doi: 10.1002/cbic.202300736)

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